Stem Cells & Regenerative Medicine

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Embryology, defined as the study of embryo development from fertilization to the fetus stage, has long been a staple in universities worldwide. However, over the last century, it has been largely overshadowed by experimental genetics and cell biology, evolving into developmental biology, which has often replaced embryology in academic settings. Recent advancements in molecular biology, biochemistry, and genomics have led to a deeper understanding of the molecular aspects of development, culminating in the emergence of stem-cell biology. This integrated approach combines embryology and development at the molecular level, utilizing engineering, imaging, and cell culture techniques. The focus of this book is on the fundamental developmental, cellular, and molecular biological aspects of stem cells and their clinical applications in tissue engineering and regenerative medicine. It delves into the biology of embryonic and cancer cells, their roles in self-renewal, muscle repair, epigenetic processes, and therapeutic uses. Additionally, it addresses significant topics such as nuclear reprogramming, induced pluripotency, and innovative stem cell culture techniques with novel biomaterials. This comprehensive introduction to stem-cell biology serves as a vital resource for graduate students, post-docs, professors, and professionals in biotech and pharmaceutical industries.