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This text discusses the functions of Process R&D (research and development), which involves the method of transforming a research synthetic procedure into a plant process and the key aspects of a synthesis that must be considered when scaling up a process. Topics consist basic principles of chemical development; techniques for the minimization of by-product impurities; criteria for cost-effective synthesis of enantiopure compounds by resolutions; asymmetric synthesis, and "chiral pool" strategy; synthesis for labeling substances with hydrogen or carbon isotopes; and last, licensing.
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Principles of Process Research and Chemical Development in the Pharmaceutical Industry, Oljan Repic
- Langue
- Année de publication
- 1998
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- Titre
- Principles of Process Research and Chemical Development in the Pharmaceutical Industry
- Langue
- Anglais
- Auteurs
- Oljan Repic
- Éditeur
- Wiley-Interscience
- Publié
- 1998
- Format
- rigide
- Pages
- 273
- ISBN10
- 0471165166
- ISBN13
- 9780471165163
- Séries
- Mots clés
- Nonfiction, Santé & Médecine, Science et Mathématiques, Médecine, Sciences naturelles, Chimie
- Description
- This text discusses the functions of Process R&D (research and development), which involves the method of transforming a research synthetic procedure into a plant process and the key aspects of a synthesis that must be considered when scaling up a process. Topics consist basic principles of chemical development; techniques for the minimization of by-product impurities; criteria for cost-effective synthesis of enantiopure compounds by resolutions; asymmetric synthesis, and "chiral pool" strategy; synthesis for labeling substances with hydrogen or carbon isotopes; and last, licensing.