W. Jänig Livres

Cook et al. discuss Phospholipases C and D in mitogenic signal transduction. Moolenaar examines lysophosphatidic acid, a bioactive phospholipid with growth factor-like properties. Kozma focuses on serine/threonine kinases in the propagation of the early mitogenic response. Diringer provides a retrospective on transformation, growth control, and some peculiarities of lipid metabolism. Villereal explores calcium signals in growth factor signal transduction. Wakabayashi analyzes the structure and function of the growth factor-activatable Na+/H+ exchanger. Herrlich addresses DNA damage-induced gene signal transduction and its relation to growth factor signaling. Lucibello discusses transcription factor-encoding oncogenes.

"Fundamentals of Neurophysiology" explores the foundations of the nervous system, including the structure of nerve cells, supporting and nourishing tissues, and the anatomy of the central nervous system. It addresses the excitation of nerves and muscles, discussing resting potential, sodium pumps, and action potentials. The kinetics of excitation and the propagation of action potentials are also examined. Synaptic transmission is explained through the neuromuscular junction and the quantum nature of chemical transmission, followed by an overview of central excitatory and inhibitory synapses. The physiology of small neuron connections and reflexes includes typical neuronal circuits as well as monosynaptic and polysynaptic motor reflexes. The section on muscles discusses muscle contraction, its dependence on fiber length and shortening velocity, as well as electromechanical coupling and the regulation of contraction. Motor systems encompass spinal motor control, the roles of muscle spindles and Golgi tendon organs, polysynaptic motor reflexes, the functional anatomy of supraspinal motor centers, and the reflexive control of body posture. Finally, the sensory system is addressed, explaining the fundamentals of sensory perception and processing within the nervous system.