Handbook of Experimental Pharmacology - 85: The Pharmacology of Lymphocytes

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This volume provides a comprehensive survey of the rationale, techniques and contemporary understanding of those drugs which have significant immunomodulatory activity. Major features of the volume an overview of current understanding of the biochemistry of lymphocyte activation, an extensive description of the methodology required for study of lymphocytes and their products; coverage of the interaction between lymphocytes and selected hormones; a synopsis of the current understanding of drugs designed to modify lymphocyte function; and an assessment of the prospects for selecting drugs which might modify the immune response. By presenting immunology as a discipline amenable to investigation by pharmacologists, and in view of the current detailed understanding of molecular mechanisms in immunology, immunotherapy is promised increased attention. This volume summarizes the extent to which such expectations have been fulfilled and allows an assessment of the prospects for progress in lymphocyte pharmacology.