Ronald D. Smith Livres

This second edition offers step-by-step processes for strategic communication activities, including planning, research, implementation, and evaluation. For students and practitioners in public relations.

The sixth edition of Becoming a Public Relations Writer continues its place as an essential guide to the writing process for public relations practice. Smith provides comprehensive examples, guidelines and exercises that allow students to both learn the fundamentals of public relations writing and practice their writing skills. Ethical and legal issues are woven throughout the text, which covers public relations writing formats for both journalistic and organizational media. This new edition updates and expands its coverage of writing for digital and social media―including blogs, websites and wikis, as well as social networking (Facebook), microblogging (Twitter), photo sharing (Instagram and Snapchat) and video sharing (YouTube). This range reflects the current landscape of public relations writing, preparing undergraduate students for a public relations career. Becoming a Public Relations Writer is a trusted resource for courses in public relations, media writing and strategic communication. Previous editions of this text have been adopted by more than 190 colleges and universities in the U.S. and among other English-speaking nations. Complementary online materials are provided for both instructors and students; instructors have access to support materials such as test banks, chapter overviews and a sample syllabus, while students will benefit from career prep resources such as ethics codes, an overview of professional organizations and sample news packages. Visit the Companion Website at www.routledge.com/cw/smith.

Revised edition of the author's Becoming a public relations writer, 2012.

Calcium Entry Blockers (CEBs) are a new class of drugs which have been pushing back the frontiers of science and medicine for almost two decades. This report reviews some of the wealth of chemical, biological and clinical data describing the discovery and development of these compounds. The scientific importance, therapeutic benefit and marketing potential of these compounds have caused an explosion of scientific literature describing their effects in many preclinical and clinical settings. The definitional characteristics of these compounds suggest a certain predictability of their biological profile but their therapeutic usefulness varies widely dependent upon their physical properties, net hemodynamic effects, duration of action and incidence of side effects. CEBs appear uniquely suited to the treatment of the underlying complexity of cardiovascular disease. The CEBs of the future may live up to the expectations of pathophysiologically based therapeutics and allow the heart and blood vessels to outlive the cells which they support. The development of CEBs is an evolving story of epic proportions and represents the cooperative efforts of individuals in all areas of science. Inhaltsverzeichnis Abstracts.- 1 Introduction: Calcium Entry Blockers (CEBs).- 1.1 History of Calcium Entry Blocker New Drug Discovery.- 1.2 Nomenclature and Classification.- 1.3 Definitional Characteristics.- 1.4 Screening Philosophy.- 1.5 Methodological Notes for Screening Vascular Effects.- 2 Current Calcium Entry Blocker.- 2.1 Status of CEB New Drug Discovery.- 2.2 Additional Sites of Action.- 3 Preclinical Pharmacology.- 3.1 Vasodilator Effects of CEBs.- 3.2 Antihypertensive Effects of CEBs.- 3.3 CEB Effects on Myocardial Rate and Rhythm.- 3.4 Anti-Ischemic/Myocardial Protective Effects of CEBs.- 3.5 Cytoprotective Effects of CEBs in Hepatic Injury.- 3.6 Cytoprotective Actions of CEBs in Models of Cerebral Ischemic Injury.- 3.7 Effects of CEBs on Airway Smooth Muscle and Mast Cell Mediator Release.- 3.8 CEBs in Atherosclerosis.- 3.9 Effects of CEBs on Platelet Aggregation.- 3.10 Effects of CEBs on Red Blood CElls.- 3.11 CEBs and Neutrophil Function.- 3.12 Endocrine Effects of CEBs.- 4 Therapeutic Indications.- 4.1 Angina Pectoris.- 4.2 Arterial Hypertension.- 4.3 Vascular Disease.- 4.4 Congestive Heart Failure.- 4.5 Myocardial Arrhythmias.- 4.6 Asthma.- 4.7 Other Therapeutic Indications.- 5 Adverse Effects.- 6 Perspectives: CEB New Drug Discovery.- 7 Acknowledgement.- 8 References.- Author Index Volumes 1 6.

Approaches and techniques of clinical epidemiology have become increasingly prominent in veterinary literature. This second edition of Veterinary Clinical Epidemiology: A Problem-Oriented Approach reflects the increasing recognition of the role of clinical epidemiology by focusing on the application of epidemiologic principles and techniques of problems regularly faced by veterinary practitioners. Numerous examples from veterinary literature indicate how experience with patients can be used to explore issues of importance in the practice of veterinary medicine while controlling for bias, confounding, and chance. The first part of the book focuses on the application of epidemiology in medical decision-making, while the second part focuses on the epidemiology of disease in populations and outbreak investigation. Included in this text are a glossary and an extensive bibliography, as well as myriad updates to reflect the expanding use of epidemiologic methodology in clinical research. Veterinary Clinical Epidemiology: A Problem-Oriented Approach serves as both a teaching resource for veterinary epidemiology and a reference on the application of epidemiologic methods in veterinary clinical research.