Handbook of toxicogenomics

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Toxicogenomics is a dynamic and promising field that enhances toxicity analyses and research into active substances, relevant for both basic research and legal/ethical considerations. This interdisciplinary overview offers solid information from an international team of experienced authors, making it valuable for those developing research strategies. Contributors hail from major research institutions like the Fraunhofer Institute of Toxicology and Experimental Medicine (Germany), the German Cancer Research Center, and the National Institute of Environmental Health Science (USA), as well as companies such as Affymetrix, Bayer, and Novartis. The content covers technology platforms like DNA arrays and proteomics, necessary bioinformatics tools, and applications of toxicogenomics illustrated through numerous case studies. It also includes insights into national programs, initiatives, and regulatory perspectives. Walter Rosenthal, Director of the Research Institute for Molecular Pharmacology in Berlin, commends the handbook for addressing a highly relevant topic and for featuring leading experts. He highlights how modern genomic research is driving rapid advancements and new insights in toxicology.