Clinical pharmacology of sleep

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Since the mid-1970s, when the Stanford Sleep Disorders Clinic was established, clinical sleep medicine has expanded significantly, addressing the diagnostic and treatment needs of patients with various sleep disorders. The treatment landscape now includes a variety of pharmacological agents—traditional, non-traditional, over-the-counter, and prescription medications—used to manage a range of clinically recognized sleep disorders. While numerous academic works discuss individual treatment options, no comprehensive resource has focused on pharmacological strategies for major sleep disorders linked to various symptoms. This volume uniquely addresses this gap, featuring chapters on diverse conditions, from pediatric sleep disorders to those related to Alzheimer’s dementia, highlighting the application of drug therapy in sleep medicine. The editors have assembled a distinguished group of sleep clinicians and researchers who provide an in-depth analysis of common sleep disorders suitable for pharmacological intervention. Each chapter includes a historical overview of the disorder and reviews foundational pre-clinical studies that inform current treatment options, offering a state-of-the-art perspective on the intersection of sleep disorders and pharmacotherapy.