Prenatal diagnosis and treatment of spina bifida

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In this issue the authors from The Children’s Hospital of Philadelphia along with international colleagues share findings and present best practices gleaned from – and subsequent to – the MOMS (Management of Myelomeningocele Study) trial. They provide a detailed account of the specific roles the different diagnostic and imaging modalities [maternal serum alpha-fetoprotein (MSAFP), ultrasound, magnetic resonance imaging (MRI), and echocardiography] played in diagnosis, treatment, and monitoring. Nuances of the fetal myelomeningocele (MMC) repair technique and long-term urologic functional outcomes as well as the progress towards fetal MMC repair using tissue engineering techniques are evaluated and analyzed in this publication. Find out about the fetal MMC repair outcomes at The Children’s Hospital of Philadelphia since the MOMS trial concluded! This issue is directed at obstetricians, maternal-fetal medicine specialists, pediatric surgeons, neurosurgeons, neonatologists, radiologists, anesthesiologists, cardiologists, geneticists, pediatricians, nurses, and social workers who play a crucial role within the multidisciplinary teams that manage fetuses with anatomic or genetic defects.