The Origin of Chronic Inflammatory Systemic Diseases and Their Sequelae

Chronic inflammatory diseases trigger a systemic response that affects the entire body, activating common pathways that regulate energy and water balance. Over time, this response can lead to a range of complications, including fatigue, depressive symptoms, sleep issues, malnutrition, and muscle wasting. Additional consequences may involve insulin resistance, hormonal disturbances, increased sympathetic tone, hypertension, and inflammation-related anemia. The book explores these interconnected issues, emphasizing how stress can exacerbate symptoms and affect circadian rhythms in patients.