Reprogramming the Brain

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In June 2021, a decision was made to surgically implant two six-inch-long metal alloy spikes through Ben's brain due to the unmanageable side effects of his Parkinson's disease medications. At that time, Ben was taking around 20 pills daily, each designed to activate dopamine pathways in his brain, leading to uncontrollable movements for about an hour followed by a brief period of normalcy before the tremors returned. This cycle of medication was exhausting. After months of medication adjustments and fine-tuning his deep brain stimulator, a groundbreaking clinical trial in North America allowed for the activation of adaptive settings for the first time. This narrative explores the decision-making process behind this innovative approach and the subsequent events that unfolded. Key topics include the complexities of deep brain stimulation (DBS), the roles of caregivers, the implications of letting algorithms influence brain function, and the future of neuromodulation therapies. The story reflects on the challenges faced by both patients and physicians, the evolving landscape of neurological treatments, and the potential for new therapies to transform lives.