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RYOJI NOYORI, born in Kobe in 1938, accepted the challenge to look back upon his life. He saw himself living in poverty and often struggling during and after WW II. He saw his parents and their friends guiding and inspiring him. He saw himself climbing up the ranks at the universities in Kyoto and Nagoya, deeply embedded in the Japanese culture. He saw himself conquering organic synthesis and asymmetric homogeneous catalysis as well as green chemistry. Formative was his time with Nobel laureate E. J. Corey at Harvard where he was exposed to a completely different culture. Back in Nagoya, Noyori’s scientific success continued and culminated in receiving the Nobel Prize in 2001. His extraordinary care about Japan’s science led to his second career, first as President of RIKEN, Japan’s largest research institution, and then as a leading figure to many governmental and industrial organizations. The basis of all his activities is a deep sense of responsibility for the society at large and the next generation of scientists.