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This comprehensive work explores critical aspects of brain edema, its pathophysiology, and clinical implications. It begins with an examination of the biochemical and physiological factors contributing to brain edema, alongside advancements in computer tomography for diagnosing traumatic brain injuries. The pharmacological section delves into steroid therapies, analyzing the pharmacology of soluble glucocorticoids and their effects on brain edema following cold lesions, as well as comparing synthetic corticosteroid concentrations in various bodily fluids. The text further details immediate therapeutic measures for traumatic brain injuries, emphasizing emergency care, primary treatment protocols, and the importance of intracranial pressure monitoring. It also addresses complications such as neurogenic pulmonary edema and the role of CT scans in monitoring these cases. The discussion on steroids in traumatic brain injury presents retrospective studies on treatment outcomes with and without corticosteroids, highlighting ongoing controversies and new findings. Special attention is given to treatment strategies for children and adolescents. Lastly, the work covers steroid therapy for brain edema of varying origins, including dosing protocols in neurosurgery and treatments for tumor-related and inflammatory brain edema. Intensive care considerations for neurotrauma patients, including the use of catecholamines, antihypertensives,
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Das Hirnödem, Thomas Grumme
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- Année de publication
- 1984
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